NoTimeRx Nootropics

Cognitive focus,
without the crash.

Evidence-based neuro-optimization — Lion's Mane, Alpha GPC, and 7,8-DHF prescribed by U.S.-licensed providers.

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The Molecular Edge.
Data-driven protocols.

We don't do "sugar-pills." Every protocol is built on clinical data for neurogenesis and synaptic plasticity.

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Our stack

Ten supplements, four mechanisms.

Cholinergic support, BDNF/neurotrophic signaling, focus acute (amino-acid precursors), and adaptogenic mushrooms. Most are OTC supplements; a few are emerging-evidence flavones. We're explicit about which is which.

Daily focus & clarity

Dopamine precursor

L-Tyrosine 500 mg

Precursor amino acid for dopamine, norepinephrine, and epinephrine. Best for acute cognitive load under stress (sleep deprivation, cold, multitasking) — replenishes catecholamines that get burned through quickly.

  • 500 mg – 1.5 g before demanding tasks
  • Works for acute stress, not chronic
  • Avoid with MAOIs, stimulants, thyroid meds
from $24/mo Add to stack
Cholinergic

Alpha GPC 300 mg

Highly bioavailable choline source that crosses the blood-brain barrier. Increases acetylcholine synthesis — the primary neurotransmitter involved in memory, learning, and muscle contraction.

  • 300–600 mg once daily
  • Precursor to acetylcholine
  • Often used by powerlifters & athletes for "mind-muscle" connection
  • Pairs well with racetams or medicinal mushrooms
from $38/mo Add to stack

Neurotrophic & BDNF signaling

Medicinal mushroom

Lion's Mane Extract 8:1

Contains hericenones and erinacines shown to stimulate Nerve Growth Factor (NGF) synthesis. Our extract is dual-solvent and standardized to 30% beta-glucans for maximal neurotrophic effect.

  • 1000 mg once daily (standardized 8:1 extract)
  • Upregulates NGF — support for myelin and neurons
  • Wait 2–4 weeks for noticeable effect
  • Sourced from 100% fruiting bodies (no grain filler)
from $42/mo Add to stack
Cholinergic · long-lived

Citicoline (CDP-Choline) 250 mg

Intermediate in the synthesis of phosphatidylcholine. Unlike Alpha GPC which is a "burst" of choline, Citicoline provides a steadier supply and also upregulates dopamine receptors in the long term.

  • 250–500 mg once daily
  • Upregulates dopamine D1 & D2 receptors
  • Supports cell membrane phospholipid repair
  • Longer half-life than Alpha GPC
from $48/mo Add to stack

Adaptogens & emerging biologicals

Antioxidant · energy

Methylene Blue 1% Solution (Nootropic Tier)

A mitochondrial optimized cycler that acts as an electron cycler in the respiratory chain. Increases ATP production and acts as a mild MAO-A inhibitor at very low doses. (Requires physician review).

  • 5–10 mg dose (0.5–1 ml of 1% solution)
  • Improves mitochondrial efficiency
  • Absolute contraindication with SSRIs/MAOIs
  • Pharmaceutical grade USP, tested for heavy metals
from $45/mo Get started
Adaptogen

Rhodiola Rosea (3% Rosavins)

High-altitude adaptogen that prevents burnout. Blocks the degradation of dopamine and serotonin, helping you maintain "gas in the tank" during high-stress work weeks.

  • 200–500 mg daily
  • Anti-fatigue & anti-burnout
  • Fast-acting (usually within 1 hour)
  • Standardized to 3% rosavins / 1% salidroside
from $28/mo Add to stack
How it works

Personalized science. Direct to door.

01

Take the screen

Answer a few questions about your focus goals and health history. 2 minutes.

02

Provider matching

A licensed provider reviews your screening to ensure no drug interactions (like MAOIs) and builds your stack.

03

Monthly delivery

Everything arrives in a single discreet box. Manage refills and doses in your patient portal.

The mechanism

Bioavailability matters.

Most supermarket supplements use oxide forms with <10% absorption. We source high-purity lipids and small-molecule flavones that actually cross the blood-brain barrier.

Purity-first sourcing

Every batch is third-party tested for heavy metals and solvent residue. We only use CO2 extraction methods for our mushroom sclerotium.

TrkB Agonism

By using BDNF mimetics like 7,8-DHF, we bypass the need for raw protein injection, providing a path to support neurons via oral supplement.

The Choline Loop

Acetylcholine is the currency of focus. By providing both Alpha GPC and Citicoline, we support both the acute pool and the long-term density of receptors.

FAQ

Common questions.

Learn more about nootropics and brain health.

Is this the same as "Limitless"?

No. Nootropics are tools for optimization and resilience, not magic pills. Expect a 10-15% improvement in focus and clarity, and long-term support for brain health markers.

Do I need a prescription?

Most of our stack items are high-purity supplements, but we still require a provider screen to check for interactions with medications like SSRIs or blood thinners.

How long until I feel it?

Alpha GPC and L-Theanine work within 30-60 minutes. Lion's Mane and 7,8-DHF require consistent daily use for 2-4 weeks to reach steady-state neurotrophic support.

Are these safe long-term?

Yes. We focus on compounds that are either natural amino acids, mushrooms, or well-studied flavones with high safety profiles. We avoid unstudied stimulants.

Unlock your next level.
Data-driven focus.

3 minutes to your personalized stack.

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